Matrix Metalloproteinase Gene Delivery for Liver Fibrosis
نویسندگان
چکیده
منابع مشابه
Effective Prevention of Liver Fibrosis by Liver-targeted Hydrodynamic Gene Delivery of Matrix Metalloproteinase-13 in a Rat Liver Fibrosis Model
Liver fibrosis is the final stage of liver diseases that lead to liver failure and cancer. While various diagnostic methods, including the use of serum marker, have been established, no standard therapy has been developed. The objective of this study was to assess the approach of overexpressing matrix metalloproteinase-13 gene (MMP13) in rat liver to prevent liver fibrosis progression. A rat li...
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Objective Matrix Metalloproteinase (MMPs) play important roles in the structural and functional properties of reproductive organs. The aim of this study is to determine the prevalence of C-1562T Matrix Metalloproteinase-9 (rs3918242) gene polymorphism in fertile and infertile men. In addition, we aimed to determine the association between C-1562T MMP-9 and G-1575A MMP-2 gene polymorphisms. Mate...
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[This corrects the article on p. 21 in vol. 8, PMID: 28239354.].
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BACKGROUND Matrix metalloproteinases (MMPs) are believed to be involved in the pathogenesis of idiopathic pulmonary fibrosis (IPF), and MMP-7 has been described as a useful biomarker for IPF. However, little is known regarding the significance of MMP-10 as a biomarker for IPF. METHODS This observational cohort study included 57 patients with IPF. Serum MMPs were comprehensively measured in al...
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Cite this article: Abe H, Kamimura K, Yokoo T, Suda T, Kobayashi Y, Aoyagi Y (2014) Gene Therapy for Liver Fibrosis. JSM Gastroenterol Hepatol 2(3): 1028. *Corresponding author Kenya Kamimura, Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1–757 Asahimachi–dori, Chuo-ku, Niigata, Niigata, 9518510, Japan, Tel: +81 (25) 227–2207; F...
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ژورنال
عنوان ژورنال: Pharmaceutical Research
سال: 2007
ISSN: 0724-8741,1573-904X
DOI: 10.1007/s11095-007-9311-7